Sodium benzoate, with an E number of E211, is the sodium salt of benzoic acid.Introduced in 1999, it is a colorless crystalline powder that is commonly used as a food preservative because it helps in inhibiting the growth of fungus and bacteria in acidic products.
Pregnancy: Teratogenic effects. Pregnancy Category C. Animal reproduction studies have not been conducted with Caffeine and Sodium Benzoate Injection. It is also not known whether Caffeine and Sodium Benzoate Injection (caffeine alkaloid) can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.
Maternal treatment with oral sodium benzoate is recommended if serum ammonia is 1.5 to 2 times normal (Mendez-Figueroa 2010). Administration of sodium benzoate to the mother to prevent adverse events in newborns prenatally diagnosed with a UCD has also been described (Das 2009).
Side Effects & Safety When taken by mouth: Sodium is LIKELY SAFE for most people when taken by mouth appropriately. Doses less than 2.3 grams per day are safe for most adults. In some people ...
Sodium benzoate is a food preservative, and its other common function is as a prescription medication. It may be a safe ingredient in food for most individuals, or you may benefit from using it as a treatment for urea cycle disorder. However, you should be aware of the potential dangers of sodium benzoate so that you can watch for them.
Sodium benzoate; sodium phenylacetate should be infused through a different line than the one used for the infusion of other solutions or medications. If use of a separate line is not possible, the line should be flushed with at least 15 ml of saline solution before and after infusion with sodium benzoate; sodium phenylacetate.
The content of this webpage regarding sodium benzoate is that it should be avoided because it can react with other chemicals and produce a known cancer causing agent. So, asking for advice on how much to add is a bit like asking "how much poison" should I expose myself to.
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Sodium Benzoate. Sodium benzoate is a widely used preservative found in many foods and soft drinks. It is metabolized within mitochondria to produce hippurate, which is then cleared by the kidneys. Ingestion of sodium benzoate at the generally regarded as safe (GRAS) dose leads to a robust excursion in the plasma hippurate level.
The mixture of sodium benzoate and sodium phenylacetate, which is sold under several brand names, such as Ucephan and Ammonul, can cause several side effects. The more common side effects include headache, nausea, vomiting, dry mouth, appetite loss and mood changes, reports MayoClinic.com. Confusion, muscle pain, fatigue, difficulty moving, shortness of breath, seizures and convulsions are also possible.
safety evaluation of benzoic acid and sodium benzoate for the applied "other uses" in cosmetic products". Recently, the European Commission received Submission II on Benzoic acid, its salt and esters.
OSHA Vacated PELs: Sodium benzoate: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Medscape - Indication-specific dosing for Ammonul (sodium benzoate, sodium phenylacetate), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.
The effects of sodium benzoate preservative on micronucleus induction, chromosome break, and Ala40Thr superoxide dismutase gene mutation in lymphocytes were studied. Sodium benzoate concentrations of 0.5, 1.0, 1.5, and 2.0 mg/mL were treated in lymphocyte cell line for 24 and 48 hrs, respectively.
AMMONUL (sodium phenylacetate and sodium benzoate) Injection 10% per 10% is a sterile, concentrated, aqueous solution of sodium phenylacetate and sodium benzoate. Storage And Handling AMMONUL (sodium phenylacetate and sodium benzoate) Injection 10% per 10% is supplied in a single use glass vial.
Sodium Benzoate. Sodium benzoate is a widely used food and beverage preservative. 34 As a sole agent, it is not US Food and Drug Administration (FDA)-approved for medicinal use, but, since 1979, it has been used off-label to treat HE in patients with hyperammonemia, initially in those with urea cycle enzyme deficiencies and later in patients with cirrhosis.
Check with your doctor as soon as possible if any of the following side effects occur while taking electrolyte replacement solutions: Symptoms of too much sodium (salt) in the body: Convulsions (seizures) dizziness. fast heartbeat. high blood pressure. irritability. muscle twitching.
Sodium Benzoate and phenoxyethanol are two "natural" preservatives that you should be wary about having in your skin care products. Although widely used, and reported as generally safe, there are reasons to be concerned about the use of both of these ingredients.
Best Answer: sodium benzoate is the sodium salt of benzoic acid. It is commonly used as a food preservative. Benzoic acid (CAS No. 65-85-0) is a white solid that is slightly soluble in water. Sodium benzoate (CAS No. 532-32-1) is about 200 times more soluble in water. Sodium benzoate is primarily used as a preserv
Find information about common, infrequent and rare side effects of Sodium Benzoate-Sod Phenylacet Intravenous.
Sodium benzoate (E211) side effects include allergies, headaches, mitochondrial damage, and when mixed with vitamin C, it forms benzene - a carcinogen.
PubMed Citation (Among 183 patients with urea cycle disorders enrolled in a US consortium, causes included OTC deficiency [55%], ASA deficiency [16%] and citrullinemia [14%]; 63% were on a protein restricted diet, 37% phenylbutyrate and 5% sodium benzoate; no discussion of side effects).
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